We went to Alaska last year (flew to Anchorage/Drove)Anyway If you look on a map Anchorage is in the middle with Seward to the South and Denali to the north. By tain it was 4 hours from Anchorage to Seward. From Anchorage to Denali it is also a 4 hour drive north.
It would be a very long ride from one to the other, and you would still need to get to Anchorage or Fairbanks for a flight home. You don't go "around" Denali unless you pay for a charter plane- we did this with K-2 Aviation. Denali is beautiful and when our plane flew into Anchorage the pilot went close to Denali, tipped the right wing down and if you were fortunate enough to have a seat at the window (on the righthand side of the plane if you were looking from the cabin forward) you got an upclose and personal view of the mountain. In Seward we took a 1/2 day Resurrection Bay cruise to Fox Island for lunch.... loved it!