Hallo deekay,
it is a little bit difficult. Click
here for a map, where you will find your hotel. (Click on the red button to zoom the map) You can take the shuttle bus from the port to Piazzale Roma. Than go to vaporetto Linea Uno (Nr. 1)tp Piazza San Marco.
The waterbus-stop is marked on the map. Than you have to go by feet to your hotel (about 5 minutes).
Regards
Uwe