We stayed in the Hotel Centro near Termini Station when we were in Rome for 10 days prior to a cruise last November. It is within walking distance of the bus and rail station and was very handy for restaurants and for picking up the #64 bus around the main tourist sites. They will pick you up at the airport if you wish. It is about $40-45 for pickup and delivery to the airport. Going rate now for rail from Termini to FCO is about 12 euros. The website is here
. We actually booked it through here
. We had no problem with the reservation at the hotel when we arrived. They serve a very substantial continental breakfast. It doesn't change from day to day so it got a bit boring but it was overall a very good buffet. Our room was clean and quiet.