I would do it, with some caveats. Of course, I'd need to know the embarkation and debarkation ports, and the length of the cruise, which sounds like a given, anyway. I would also want shore excursions included in the deal (and guaranteed, although more adventurous pax could opt out) so that I could get the most out of the port visits, as researching ports before the cruise could prove useless. I would also want to have some guidelines as to what to pack.
Yes, this is a niche cruise that would be pretty much have to be offered as a full-ship charter.