Regarding the hotels and airport issue, there is only one hotel, The Rome Airport Hilton, which is actually located at the airport. The Hilton is actually connected to the terminal buildings via a very convenient covered overpass (you access it via an elevator about 10 feet from the front entrance of the hotel). Whenever we have a morning flight out of Rome, we always spend the night at the Hilton. This avoids any hassles with morning trains or taxis, and its pretty easy to get a luggage cart at the hotel so you wheel your baggage all the way to the ticket counter at the airport. It is a bit of a hike through the overpasses into the proper terminal, but its not a problem unless you have restrictions on your ability to walk. As to lines in Rome, things seem to vary depending on day of the week, time of the day, etc etc. But, the longest lines are usually to be found when trying to enter the Vatican Museums (this is the tour that includes the Sistine Chapel). It is sometimes possible to bypass this line if you are on an organized tour (such as the ones offered by the cruise ships). Some of the better private guides have been known to have schemes to avoid the line, but I have no personal experience with these guides. It is possible to buy a tour, in advance, from the Vatican which will bypass the lines. My understanding (we have never done this) is you have to send a fax to the Vatican about a month in advance and they will let you know if you can get on one of these tours. The info about this is on the Vatican website. You can try
http://mv.vatican.va/3_EN/pages/z-In...zi_Visite.html
for info.
Hank