One of our Canada/New England cruises was during the month of October. The seas varied -- some places were smooth while we had rough seas in another, on the same cruise! Weather up here varies. For the record, though, we've experienced worse seas in the western Caribbean, also in October/November timeframe.
The best remedy I've found for seasickness, in the off-chance you'll need it, is an apple. A crew member suggested it to me years ago.