Hello Shawn L, welcome to Cruise-Chat! My wife is prone to motion sickness too. She wears the patch behind her ear and has never had a problem. The center of the ship is suppose to be the best location, but it really doesn't seem to matter much. You'll be all over the ship, the dining room is on one end, and the theater is on another. Most of my cruises have been smooth sailing and there isn't any motion. I would wear the patch if I was worried about motion sickness. You need a prescription to get them.
Hope this helps,